Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems
Young C. Jang, Karl A. Rodriguez, Michael S. Lustgarten, Florian L. Müller, Arunabh Bhattacharya, Anson Pierce, Jeongmoon J. Choi, Nan Hee Lee, Asish R. Chaudhuri, Arlan Richardson, Holly Van Remmen
Topics & Concepts
Muscle atrophyOxidative stressSkeletal muscleSOD1CalpainProteolysisSarcopeniaAtrophyProtein degradationInternal medicineEndocrinologyChemistryProteasesProteostasisOxidative phosphorylationSuperoxide dismutaseReactive oxygen speciesMitochondrionBiochemistryCell biologyBiologyMedicineEnzymeMuscle Physiology and DisordersGenetic Neurodegenerative DiseasesMuscle metabolism and nutrition