Intraarterial Therapies for the Management of Hepatocellular Carcinoma
Tushar Garg, Apurva Shrigiriwar, Peiman Habibollahi, M. Cristescu, Robert P. Liddell, Julius Chapiro, Peter W. Inglis, Juan C. Camacho, Nariman Nezami
Abstract
Image-guided locoregional therapies play a crucial role in the management of patients with hepatocellular carcinoma (HCC). Transarterial therapies consist of a group of catheter-based treatments where embolic agents are delivered directly into the tumor via their supplying arteries. Some of the transarterial therapies available include bland embolization (TAE), transarterial chemoembolization (TACE), drug-eluting beads-transarterial chemoembolization (DEB-TACE), selective internal radioembolization therapy (SIRT), and hepatic artery infusion (HAI). This article provides a review of pre-procedural, intra-procedural, and post-procedural aspects of each therapy, along with a review of the literature. Newer embolotherapy options and future directions are also briefly discussed.