Litcius/Paper detail

Oxidation of Alkenes by Water with H<sub>2</sub> Liberation

Shan Tang, Yehoshoa Ben‐David, David Milstein

2020Journal of the American Chemical Society47 citationsDOIOpen Access PDF

Abstract

liberation is highly desirable, as it can serve as an environmentally friendly way for the oxidation of organic compounds. Herein, we report the oxidation of alkenes with water as the oxidant by using a catalyst combination of a dearomatized acridine-based PNP-Ru complex and indium(III) triflate. Compared to traditional Wacker-type oxidation, this transformation avoids the use of added chemical oxidants and liberates hydrogen gas as the only byproduct.

Topics & Concepts

ChemistryWacker processCatalysisLiberationEnvironmentally friendlyTrifluoromethanesulfonateAlkylphenolIndiumOrganic chemistryPalladiumAlkylIn vitroBiologyBiochemistryEcologyAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions