Artesunate Reduces Remifentanil-induced Hyperalgesia and Peroxiredoxin-3 Hyperacetylation via Modulating Spinal Metabotropic Glutamate Receptor 5 in Rats
Linlin Zhang, Yuying Zhao, Tianyu Gao, Haoyue Zhang, Jing Li, Jing Li, Guolin Wang, Chunyan Wang, Yize Li
Topics & Concepts
PharmacologyMetabotropic glutamate receptor 5ArtesunateChemistryHyperalgesiaNociceptionAgonistGlutamate receptorMetabotropic glutamate receptor 1AntagonistMetabotropic glutamate receptorMedicineMetabotropic receptorReceptor antagonistOxidative stressAnesthesiaNeuroprotectionNeuropathic painMetabotropic glutamate receptor 2ReceptorSpinal cordNMDA receptorPain Mechanisms and TreatmentsTreatment of Major DepressionPharmacological Receptor Mechanisms and Effects