The chemistry and biology of guanidine secondary metabolites
Roberto G. S. Berlinck, Darlon I. Bernardi, Taícia Pacheco Fill, Alessandra A. G. Fernandes, Igor D. Jurberg
Abstract
Covering: 2017-2019Guanidine natural products isolated from microorganisms, marine invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal peptides, guanidine-bearing polyketides, alkaloids, terpenoids and shikimic acid derived, are the subject of this review. The topics include the discovery of new metabolites, total synthesis of natural guanidine compounds, biological activity and mechanism-of-action, biosynthesis and ecological functions.
Topics & Concepts
GuanidineMicroorganismBiosynthesisChemistryBiologyBiochemistryGeneBacteriaGeneticsMicrobial Natural Products and BiosynthesisMarine Sponges and Natural ProductsEnzyme function and inhibition