Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma
Catherine S. Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodríguez, Petra Ross‐Macdonald, Megan Wind‐Rotolo, Ameya S. Champhekar, Egmidio Medina, Davis Y. Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie M. Campbell, Agustin Vega-Crespo, Michael J. Quist, Christophe Martignier, Jason J. Luke, Jedd D. Wolchok, Douglas B. Johnson, Bartosz Chmielowski, F. Stephen Hodi, Shailender Bhatia, William Sharfman, Walter J. Urba, Craig L. Slingluff, Adi Diab, John B.A.G. Haanen, Salvador Martín‐Algarra, Drew M. Pardoll, Valsamo Anagnostou, Suzanne L. Topalian, Victor E. Velculescu, Daniel E. Speiser, Anusha Kalbasi, Antoni Ribas
Topics & Concepts
BlockadeImmune checkpointMelanomaInterferonImmune systemTranscriptomeCancer researchImmunologyMedicineSignal transductionImmunotherapyBiologyReceptorInternal medicineGeneCell biologyGeneticsGene expressionCancer Immunotherapy and BiomarkersMelanoma and MAPK PathwaysCutaneous Melanoma Detection and Management