Cocrystal engineering of pharmaceutical solids: therapeutic potential and challenges
Si Nga Wong, Yu Chee Sonia Chen, Bianfei Xuan, Changquan Calvin Sun, Shing Fung Chow
Abstract
This highlight presents an overview of pharmaceutical cocrystal production and its potential in reviving problematic properties of drugs in different dosage forms. The challenges and future outlook of its translational development are discussed.
Topics & Concepts
CocrystalBiochemical engineeringPharmaceutical sciencesNanotechnologyCombinatorial chemistryChemistryPharmacologyEngineeringMedicineMaterials scienceOrganic chemistryMoleculeHydrogen bondCrystallography and molecular interactionsCrystallization and Solubility StudiesEnergetic Materials and Combustion