IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma
Junnan Ru, Jiahua Lu, Jiangzhen Ge, Bo Ding, Rong Su, Yifan Jiang, Yujing Sun, Jun Ma, Yu Li, Jingqi Sun, Guangming Xu, Rongliang Tong, Shusen Zheng, Beng Yang, Jian Wu
Topics & Concepts
Cancer researchPD-L1Hepatocellular carcinomaTranscription factorPhosphorylationDownregulation and upregulationMedicineImmune systemImmunotherapyCytotoxic T cellImmunologyBiologyCell biologyIn vitroBiochemistryGeneCancer Immunotherapy and BiomarkersImmune cells in cancerinterferon and immune responses