Metal-free oxidative coupling of arylmethylamines with indoles: a simple, environmentally benign approach for the synthesis of 3,3′-bis(indolyl)methanes
Vikas D. Kadu, Sankala Naga Chandrudu, Mahesh G. Hublikar, Dattatraya Raut, Raghunath B. Bhosale
Abstract
C-C and C-N bond formation. This attractive and environmentally friendly one-pot protocol is a simple procedure that features inexpensive acetic acid as the catalyst and molecular oxygen as the sole oxidant, and it supports a wide substrate scope with the good tolerance of functional groups.
Topics & Concepts
Environmentally friendlyOxidative coupling of methaneChemistryMolecular oxygenCatalysisSubstrate (aquarium)Acetic acidCombinatorial chemistryOxidative phosphorylationFunctional groupMetalOxygenOrganic chemistryBiologyGeologyEcologyBiochemistryOceanographyPolymerSynthesis of Indole DerivativesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods