Advancing pathogen detection for airborne diseases
Tingting Zhai, Yuhan Wei, Lihua Wang, Jiang Li, Chunhai Fan
Abstract
Airborne diseases including SARS, bird flu, and the ongoing Coronavirus Disease 2019 (COVID-19) have stimulated the demand for developing novel bioassay methods competent for early-stage diagnosis and large-scale screening. Here, we briefly summarize the state-of-the-art methods for the detection of infectious pathogens and discuss key challenges. We highlight the trend for next-generation technologies benefiting from multidisciplinary advances in microfabrication, nanotechnology and synthetic biology, which allow sensitive, rapid yet inexpensive pathogen assays with portable intelligent device.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPathogenMultidisciplinary approachNanotechnologyMicrofabricationData scienceComputer scienceBiologyMedicineVirologyDiseaseImmunologyPathologyFabricationSociologySocial scienceOutbreakMaterials scienceAlternative medicineBiosensors and Analytical DetectionSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniques