Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition
Sergio Crespo‐Garcia, Pamela R. Tsuruda, Agnieszka Dejda, Rathi D. Ryan, Frédérik Fournier, S. Chaney, Frédérique Pilon, Taner Dogan, Gaël Cagnone, Priyanka Patel, Manuel Buscarlet, Sonali Dasgupta, Gabrielle Girouard, Surabhi Rao, Ariel M. Wilson, Robert O’Brien, Rachel Juneau, Vera Guber, Alexandre Dubrac, Christian Beauséjour, Scott A. Armstrong, Frédérick A. Mallette, Christopher B. Yohn, Jean‐Sébastien Joyal, Dan Marquess, Pedro J. Beltran, Przemysław Sapieha
Topics & Concepts
AngiogenesisNeovascularizationSenescenceDiabetic retinopathyPathologicalBiologyRetinalCancer researchRetinopathyChoroidal neovascularizationRetinaBlood vesselApoptosisCell biologyPathologyMedicineNeuroscienceDiabetes mellitusGeneticsEndocrinologyBiochemistryRetinal Diseases and TreatmentsRetinal Development and DisordersRetinal Imaging and Analysis