Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
Youcef Mehellou
Abstract
The activation of PINK1 by small molecules has emerged as a promising strategy in treating Parkinson's disease (PD). Recent progress in this area has raised excitement around PINK1 activators as PD treatments, and herein we offer insight into these developments and their potential to deliver much needed novel PD treatments.
Topics & Concepts
PINK1Parkinson's diseaseDiseaseMedicineNeuroscienceParkinInternal medicinePsychologyParkinson's Disease Mechanisms and TreatmentsLysosomal Storage Disorders ResearchCalcium signaling and nucleotide metabolism