One-for-all intelligent core–shell nanoparticles for tumor-specific photothermal–chemodynamic synergistic therapy
Hongshuai Wu, Dihai Gu, Shengjin Xia, Fanghui Chen, Chaoqun You, Bai‐Wang Sun
Abstract
self-sufficiency. Moreover, the HA ligand could enhance the tumor accumulation of the HG-MIL@PDANPs through the long blood circulation time and CD44-targeted cell recognition. The ingenious integration of PTT and CDT in one fully equipped system presented excellent synergistic antitumor efficiency in vitro and in vivo with favorable biosafety. The one-for-all intelligent core-shell nanoparticles with CD44 targeting provide a new avenue for engineering on-demand tumor-specific therapy.
Topics & Concepts
Photothermal therapyNanoparticleChemistryCore (optical fiber)Shell (structure)NanotechnologyBiophysicsMaterials scienceBiologyComposite materialNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisNanoparticle-Based Drug Delivery