Design, synthesis, and evaluation of n-butylphthalide and ligustrazine hybrids as potent neuroprotective agents for the treatment of ischemic stroke in vitro and in vivo
Yi Jia, Haiyan Xiao, Xiaolin Wang, Ying Liu, Jiaxin Wang, Haochen Xie, Hai Shang, Guibo Sun, Yu Tian
Topics & Concepts
NeuroprotectionPharmacologyIn vivoChemistryApoptosisIschemiaIn vitroMitochondrionStroke (engine)BiochemistryMedicineBiologyInternal medicineBiotechnologyMechanical engineeringEngineeringNeurological Disease Mechanisms and TreatmentsTraditional Chinese Medicine AnalysisNeuroinflammation and Neurodegeneration Mechanisms