Revised model of the tissue factor pathway of thrombin generation: Role of the feedback activation of FXI
Hari Hara Sudhan Lakshmanan, Aldrich Estonilo, Stéphanie E. Reitsma, Alexander R. Melrose, Jayaram Subramanian, Tony J. Zheng, Jeevan Maddala, Erik I. Tucker, David Gailani, Owen J. T. McCarty, Patrick Jurney, Cristina Puy
Topics & Concepts
ThrombinTissue factorSerine proteaseThrombin generationCoagulationChemistryAntithrombinsPlatelet activationFactor IXFactor XIProteaseCell biologyBiochemistryBiologyPlateletImmunologyEnzymeMedicineInternal medicineCoagulation, Bradykinin, Polyphosphates, and AngioedemaBlood Coagulation and Thrombosis MechanismsHemophilia Treatment and Research