Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors
Jingke Fu, Tao Li, Yangzi Yang, Liping Jiang, Wenhao Wang, Lingjie Fu, Yingchun Zhu, Yongqiang Hao
Topics & Concepts
DoxorubicinApoptosisMultiple drug resistanceCancer researchNanomedicineProgrammed cell deathHypoxia (environmental)Tumor hypoxiaTumor microenvironmentChemotherapyReactive oxygen speciesDrug resistanceChemistryPharmacologyMaterials scienceMedicineBiologyRadiation therapyBiochemistryTumor cellsNanotechnologyOxygenInternal medicineNanoparticleMicrobiologyOrganic chemistryNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseNanoparticle-Based Drug Delivery