Fabrication of Biohybrid Cellulose Acetate-Collagen Bilayer Matrices as Nanofibrous Spongy Dressing Material for Wound-Healing Application
Giriprasath Ramanathan, Liji Sobhana Seleenmary Sobhanadhas, Grace Felciya Sekar Jeyakumar, Mohan Vimala Devi, Uma Tiruchirapalli Sivagnanam, Pedro Fardim
Abstract
biological and fluorescence properties of the matrix were tested against NIH 3T3 fibroblast and human keratinocyte (HaCaT) cell lines and showed good cell adhesion and proliferation over the bilayer matrix. Thus, the synergistic combination of nanofibrous material deposition onto to the collagenous porous material has proved efficient in the fabrication of a bilayer matrix for skin-tissue-engineering applications.
Topics & Concepts
ElectrospinningBilayerTissue engineeringMaterials scienceChemical engineeringNanofiberCellulose acetateBiomaterialSwellingPolymer chemistryPolymerNanotechnologyComposite materialChemistryBiomedical engineeringMembraneCelluloseBiochemistryEngineeringMedicineElectrospun Nanofibers in Biomedical ApplicationsSilk-based biomaterials and applicationsBone Tissue Engineering Materials