Self-assembled polymeric nanoparticles for redox- and gene-regulated osteoarthritis therapy
Bing Wu, Yang Ye, Xiancheng Huang, Yuanchao Shi, Chongzhou Fang, Fei Liu, Yang-Chi-Dung Lin, Jiaxin Wang, Jianjing Lin, Jing Mu, Xintao Zhang, Xintao Zhang
Topics & Concepts
OsteoarthritisCartilageReactive oxygen speciesGene silencingInflammationSmall interfering RNAOxidative stressExtracellular matrixCancer researchCell biologySuperoxide dismutaseCatabolismChemistryDownregulation and upregulationRNA interferenceGene expressionTransfectionMedicineMaterials scienceCartilage damageIn vitroMatrix metalloproteinaseHyaluronic acidPharmacologyGenetic enhancementTherapeutic gene modulationExtracellularIn vivomicroRNAOsteoarthritis Treatment and MechanismsAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranostics