Comparison between twin-screw and high-shear granulation - The effect of filler and active pharmaceutical ingredient on the granule and tablet properties
Kaisa Kyttä, Satu Lakio, Håkan Wikström, Anisa Sulemanji, Magnus Fransson, Jarkko Ketolainen, Pirjo Tajarobi
Topics & Concepts
GranulationGranule (geology)Microcrystalline celluloseUltimate tensile strengthMaterials scienceComposite materialFriabilityParticle sizeExcipientTabletingParticle-size distributionChromatographyChemical engineeringChemistryCellulosePolymerEthyl celluloseOrganic chemistryEngineeringDrug Solubulity and Delivery SystemsGranular flow and fluidized bedsProtein purification and stability