Virtual discovery of melatonin receptor ligands to modulate circadian rhythms
Reed M. Stein, Hye Jin Kang, John D. McCorvy, Grant C. Glatfelter, Anthony Jones, Tao Che, Samuel T. Slocum, Xi‐Ping Huang, Olena Savych, Yurii S. Moroz, Benjamin Stauch, Linda C. Johansson, Vadim Cherezov, Terry Kenakin, John J. Irwin, Brian K. Shoichet, Bryan L. Roth, Margarita L. Dubocovich
Topics & Concepts
Circadian rhythmInverse agonistMelatoninCircadian clockSuprachiasmatic nucleusBiologyMelatonin receptorReceptorLight effects on circadian rhythmPineal glandG protein-coupled receptorAgonistCell biologyNeuroscienceBiochemistryCircadian rhythm and melatoninReceptor Mechanisms and SignalingFree Radicals and Antioxidants