A Small Molecule CCR2 Antagonist Depletes Tumor Macrophages and Synergizes with Anti–PD-1 in a Murine Model of Cutaneous T-Cell Lymphoma (CTCL)
Xuesong Wu, Rajinder Singh, Daniel K. Hsu, Yan Zhou, Sebastian Yu, Dan Han, Zhenrui Shi, Mindy Huynh, James J. Campbell, Samuel Hwang
Topics & Concepts
Tumor microenvironmentCCR2CD8ChemokineCancer researchImmune systemT cellMonocyteImmunologyChemokine receptorMedicineBiologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesLymphoma Diagnosis and Treatment