A mutation in p62 protein (p. R321C), associated to Paget's disease of bone, causes a blockade of autophagy and an activation of NF-kB pathway
Ricardo Usategui‐Martín, Nerea Gestoso-Uzal, Ismael Calero‐Paniagua, José M. de Pereda, Javier del Pino‐Montes, Rogelio González‐Sarmiento
Topics & Concepts
Paget's disease of boneSequestosome 1MutationProtein Data Bank (RCSB PDB)AutophagyBone resorptionExonCancer researchBiologyGeneticsGeneMedicineInternal medicineDiseaseApoptosisBiochemistryAutophagy in Disease and TherapyBone health and treatmentsHistone Deacetylase Inhibitors Research