Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy
Quansheng Cheng, Qingcheng Wang, Songnan Qu
Abstract
A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting, pH response, near-infrared fluorescence imaging, and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immunotherapy.
Topics & Concepts
PyroptosisCancer immunotherapyDual (grammatical number)ImmunotherapyCancerNanotechnologyOptoelectronicsMaterials scienceMedicineChemistryApoptosisProgrammed cell deathBiochemistryLiteratureInternal medicineArtNanoplatforms for cancer theranosticsHeme Oxygenase-1 and Carbon MonoxideFerroptosis and cancer prognosis