Litcius/Paper detail

Microorganisms and Antibiogram Patterns in Fournier’s Gangrene: Contemporary Experience from a Single Tertiary Care Center

Clara M. Castillejo Becerra, Christopher Jaeger, Justin Rose, Nicholas Beecroft, Nayan Shah, Tasha Posid, Lawrence C. Jenkins, Nima Baradaran

2020The Journal of Urology30 citationsDOI

Abstract

PURPOSE: We evaluate the prevalent microorganisms, antibiotic sensitivity patterns and associated outcomes in patients with Fournier's gangrene. MATERIALS AND METHODS: A retrospective chart review of patients with Fournier's gangrene was conducted between October 2011 and April 2018 at our institution. Univariate analysis was performed using the independent t-test or Kruskal-Wallis H test for continuous variables and exact test for categorical variables. RESULTS: were resistant to vancomycin. The overall Fournier's gangrene mortality count was 14 (10%) patients. No association was noted between the type of infection and Fournier's gangrene severity index, length of hospital stay or mortality. CONCLUSIONS: is a prevalent pathogen in the wound culture of patients with Fournier's gangrene. The resistance patterns for clindamycin and vancomycin are concerning. Addition of an antifungal agent to the empiric treatment should be considered based on clinical presentation.

Topics & Concepts

MedicineAntibiogramFournier gangreneTertiary careCenter (category theory)GangreneGeneral surgeryMicrobiologySurgeryAntibioticsAntibiotic resistanceBiologyNecrotising fasciitisChemistryCrystallographyFasciitisStreptococcal Infections and TreatmentsPressure Ulcer Prevention and ManagementNeonatal and Maternal Infections