Gastric Bypass Increases Circulating Bile Acids and Activates Hepatic Farnesoid X Receptor (FXR) but Requires Intact Peroxisome Proliferator Activator Receptor Alpha (PPARα) Signaling to Significantly Reduce Liver Fat Content
Guilherme S. Mazzini, Jad Khoraki, Matthew G. Browning, Jilin Wu, Huiping Zhou, Elvin T. Price, Luke G. Wolfe, Martin J. Mangino, Guilherme M. Campos
Topics & Concepts
Internal medicineEndocrinologyFarnesoid X receptorSteatosisMedicinePeroxisome proliferator-activated receptorFatty liverBile acidReceptorNuclear receptorChemistryDiseaseGeneTranscription factorBiochemistryLiver Disease Diagnosis and TreatmentBariatric Surgery and OutcomesOrgan Transplantation Techniques and Outcomes