Litcius/Paper detail

Light control of RTK activity: from technology development to translational research

Anna V. Leopold, Vladislav V. Verkhusha

2020Chemical Science18 citationsDOIOpen Access PDF

Abstract

with light. Light irradiation can control RTK signaling non-invasively, in a dosed manner, with high spatio-temporal precision, and without the side effects of conventional treatments. Here we provide an update on the current state of the art of optogenetic and optochemical RTK technologies and the prospects of their use in translational studies and therapy.

Topics & Concepts

Control (management)Small moleculeComputational biologyChemistryCell biologyComputer scienceBiologyBiochemistryArtificial intelligencePhotochromic and Fluorescence ChemistryRetinal Development and DisordersLight effects on plants