Salinomycin inhibits SREBP1 to sensitize ferroptosis and ameliorate sorafenib resistance in clear cell renal cell carcinoma

Su Jeong Yu, Xuan Liu, Dekun Wang, Gang Li, Xue Mi, Yuying Zhang, Shijing Yue, Zhujun Zhang, Tianyu Shen, Xiaoyue Tan

2025Biochimica et Biophysica Acta (BBA) - Molecular Cell Research6 citationsDOI

Topics & Concepts

SalinomycinSorafenibRenal cell carcinomaCancer researchMedicineCellInternal medicineAxitinibOncologyPharmacologyChemistryHepatocellular carcinomaBiochemistryAntibioticsFerroptosis and cancer prognosisCancer, Lipids, and MetabolismRenal cell carcinoma treatment