Litcius/Paper detail

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

François Ghiringhelli, Lionel Apétoh, Antoine Tesnière, Laetitia Aymeric, Yuting Ma, Carla Ortiz, Karim Vermaelen, Theocharis Panaretakis, Grégoire Mignot, Evelyn Ullrich, Jean‐Luc Perfettini, F. Schlemmer, Ezgi Tasdemir, Martin Uhl, Pierre Génin, Ahmet Civas, Bernhard Ryffel, Jean Kanellopoulos, Jürg Tschopp, Fabrice André, Rosette Lidereau, Nicole M. McLaughlin, Nicole M. Haynes, Mark J. Smyth, Guido Kroemer, Laurence Zitvogel

2009Nature Medicine1,840 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomePurinergic receptorAcquired immune systemInnate immune systemImmune systemPyrin domainImmunologyCancer researchCD8Common gamma chainBiologyReceptorMedicineInterleukin 10InflammationInternal medicineInflammasome and immune disordersAdenosine and Purinergic SignalingImmune Cell Function and Interaction