Dual Orexin Receptor Antagonists and Suicide Risk
Francesco Salvo, Jean‐Arthur Micoulaud‐Franchi, Laura Palagini, Pierre A. Geoffroy
Abstract
According to the WHO pharmacovigilance database, suicidal behavior was 1.3 times more frequent than expected with dual orexin receptor antagonists and 4.7 times more frequent for Z-drugs; data on lemborexant were sparse.
Topics & Concepts
PharmacovigilanceOrexinDual (grammatical number)PharmacologyMedicinePoison controlReceptorPsychiatryPsychologyInternal medicineMedical emergencyDrugArtLiteratureNeuropeptideSleep and Wakefulness ResearchSleep and related disorders