Impacts of noncovalent interactions involving sulfur atoms on protein stability, structure, folding, and bioactivity
Volga Kojasoy, Dean J. Tantillo
Abstract
This review discusses the various types of noncovalent interactions in which sulfur atoms participate and their effects on protein stability, structure, folding and bioactivity. Current approaches and recommendations for modelling these noncovalent interactions (in terms of both geometries and interaction energies) are highlighted.
Topics & Concepts
Non-covalent interactionsFolding (DSP implementation)SulfurProtein foldingChemistryBiophysicsCrystallographyComputational chemistryChemical physicsNanotechnologyMoleculeBiochemistryBiologyMaterials scienceHydrogen bondOrganic chemistryEngineeringElectrical engineeringPeptidase Inhibition and AnalysisEnzyme Structure and FunctionBiochemical and Molecular Research