A novel GSK-3 inhibitor binds to GSK-3β via a reversible, time and Cys-199-dependent mechanism
Davoud Ghazanfari, Mahboubeh S. Noori, Stephen C. Bergmeier, Jennifer V. Hines, Kelly D. McCall, Douglas J. Goetz
Topics & Concepts
ChemistryMechanism (biology)GSK-3StereochemistryBiophysicsBiochemistryPhosphorylationPhilosophyEpistemologyBiologyWnt/β-catenin signaling in development and cancerRadiopharmaceutical Chemistry and ApplicationsCancer-related gene regulation