Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through GAPDH- and Hsp90-dependent control of their heme levels
Pranjal Biswas, Yue Dai, Dennis J. Stuehr
Topics & Concepts
HemeIndoleamine 2,3-dioxygenaseKynurenineChemistryBiochemistryKynurenine pathwayGlyceraldehyde 3-phosphate dehydrogenaseIntracellularCell biologyTryptophanEnzymeBiologyDehydrogenaseAmino acidTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms