Restorative effects of (+)-epicatechin in a rodent model of aging induced muscle atrophy: underlying mechanisms
Israel Ramírez‐Sánchez, Viridiana Navarrete-Yañez, Lucia Ramirez, Leonor Galera, Enrique Méndez-Bolaina, Veronica Najera, Guillermo Ceballos, Francisco Villarreal
Abstract
controls. In conclusion, +Epi has the capacity to reverse sarcopenia associated detrimental changes in regulatory pathways leading to improved SkM mass and function. Given these results and its recognized safety and tolerance profile, +Epi warrants consideration for clinical trials.
Topics & Concepts
RodentRodent modelMuscle atrophyAtrophyNeuroscienceBiologyMedicineInternal medicineEndocrinologyEcologyMuscle Physiology and DisordersAdipose Tissue and MetabolismExercise and Physiological Responses