Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7–11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9
Alice Bochel, Christopher Williams, Airlie J. McCoy, H. H. Hoppe, Ashley J. Winter, Ryan Nicholls, Karl Harlos, E. Yvonne Jones, Imre Berger, A. Bassim Hassan, Matthew P. Crump
Topics & Concepts
Mannose 6-phosphateInsulin-like growth factor 2 receptorMannoseMannose 6-phosphate receptorHistidineChemistryTransmembrane domainGlycanReceptorTransmembrane proteinBiochemistryBiophysicsBiologyGlycoproteinAmino acidGrowth factorLysosomeEnzymeInsulin-like growth factor 1 receptorLysosomal Storage Disorders ResearchCellular transport and secretionErythrocyte Function and Pathophysiology