Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants
Liis Leitsalu, Marili Palover, Timo Tõnis Sikka, Anu Reigo, Mart Kals, Kalle Pärn, Tiit Nikopensius, Tōnu Esko, Andres Metspalu, Peeter Padrik, Neeme Tõnisson
Topics & Concepts
BiobankGenetic testingBreast cancerGenetic counselingMedicineCohortGenotypeOvarian cancerPopulationFamily historyRisk assessmentCohort studyOncologyGynecologyCancerInternal medicineGeneticsBiologyGeneEnvironmental healthComputer securityComputer scienceBRCA gene mutations in cancerGenomics and Rare DiseasesCRISPR and Genetic Engineering