Litcius/Paper detail

A machine learning-enabled process optimization of ultra-fast flow chemistry with multiple reaction metrics

Dogancan Karan, Guoying Chen, Nicholas A. Jose, Jiaru Bai, Paul McDaid, Alexei A. Lapkin

2023Reaction Chemistry & Engineering25 citationsDOIOpen Access PDF

Abstract

An automated flow chemistry platform was designed to collect data for a lithium-halogen exchange reaction. The data was used to train a Bayesian multi-objective optimization algorithm to optimize the process parameters and build process knowledge.

Topics & Concepts

Computer scienceBayesian optimizationProcess (computing)Flow chemistryProcess optimizationHalogenFlow (mathematics)Machine learningArtificial intelligenceChemistryContinuous flowBiochemical engineeringChemical engineeringEngineeringMathematicsProgramming languageOrganic chemistryAlkylGeometryInnovative Microfluidic and Catalytic Techniques InnovationAdvanced Control Systems OptimizationProcess Optimization and Integration