Platycodin D induces apoptotic cell death through PI3K/AKT and MAPK/ERK pathways and synergizes with venetoclax in acute myeloid leukemia
Xia Jiang, Ye Lin, Mengting Zhao, Youhong Li, Peipei Ye, Renzhi Pei, Ying Lu, Lei Jiang, Lei Jiang
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayMAPK/ERK pathwayMyeloid leukemiaCancer researchViability assayKinaseApoptosisCell cycleChemistryCell cycle checkpointBiologyBiochemistryAcute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processesCell death mechanisms and regulation