The impact of earth-abundant metals as a replacement for Pd in cross coupling reactions
Michael U. Luescher, Fabrice Gallou, Bruce H. Lipshutz
Abstract
Initial calculations of environmental footprints associated with using Ni vs Pd catalysis in a representative metal-catalyzed Suzuki–Miyaura cross-coupling reveal that the choice of ligated metal is often NOT of consequence. Rather, it is a culmination of other parameters such as medium.
Topics & Concepts
Earth (classical element)Coupling (piping)Heavy metalsPalladiumAlkaline earth metalCoupling reactionChemistryAstrobiologyEnvironmental chemistryMetalCatalysisMaterials scienceMetallurgyPhysicsBiochemistryOrganic chemistryMathematical physicsCatalytic Cross-Coupling ReactionsRadioactive element chemistry and processingChemical Reactions and Isotopes