Anti-senescent effects of long non-coding RNA H19 on human dermal fibroblast cells through impairing microRNA-296-5p-dependent inhibition of IGF2
Hua Tang, Fang Yao, Ming Yin, Yangying Liao, Ke Li, Lan Li, Xiao Xiao, Junweichen Guo, Feng Hu, Hao Feng
Topics & Concepts
Downregulation and upregulationSenescenceGene knockdownPI3K/AKT/mTOR pathwayGene silencingmicroRNACell biologyCell growthBiologyEctopic expressionChemistryCancer researchSignal transductionCell cultureBiochemistryGeneticsGeneCancer-related molecular mechanisms researchRNA regulation and diseasemelanin and skin pigmentation