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NAD(H) and NADP(H) in plants and mammals

Danying Lu, Murray Grant, Boon Leong Lim

2025Molecular Plant22 citationsDOIOpen Access PDF

Abstract

, and metabolic reactions for the reduction and oxidation of NAD(P)H. We also review the regulation of pyridine nucleotide pools and their ratios in different plant subcellular compartments and the effects of light on these ratios. We discuss the advantages of having both NADH and NADPH systems, highlight current gaps in our understanding of NAD(P)H metabolism, and propose research approaches that could fill in those gaps. The knowledge about NADH and NADPH systems could be used to guide bioengineering strategies to optimize redox-regulated processes and improve energy-use efficiency in crop plants.

Topics & Concepts

BiologyNAD+ kinaseBiochemistryEnzymeAmino Acid Enzymes and MetabolismPlant nutrient uptake and metabolismAmmonia Synthesis and Nitrogen Reduction
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