Staem5: A novel computational approach for accurate prediction of m5C site
Di Chai, Cangzhi Jia, Jia Zheng, Quan Zou, Fuyi Li
Abstract
. Staem5 was developed by employing feature fusion tactics to leverage informatic sequence profiles, and a stacking ensemble learning framework combined five popular machine learning algorithms. Extensive benchmarking tests demonstrated that Staem5 outperformed state-of-the-art approaches in both cross-validation and independent tests. We provide the source code of Staem5, which is publicly available at https://github.com/Cxd-626/Staem5.git.
Topics & Concepts
Computer scienceLeverage (statistics)Computational biologyArtificial intelligenceMachine learningData miningBiologyRNA modifications and cancerRNA and protein synthesis mechanismsGenomics and Phylogenetic Studies