Safety and Efficacy of an Innovative Airway Clearance Device Versus Manual Chest Physiotherapy Techniques For Airway Secretion Clearance: a Feasibility Study
P. Giovannetti, Laurent Morin, Martine Reynaud‐Gaubert, C Castellani, Aja Duff, S Bell, M Mcilwaine, J Bradley, J Elborn, M Mcilwaine, Lee Son, N Richmond, M, P Flume, K Robinson, O' Sullivan, B, L Warnock, A Gates, D Giles, J Wagener, F Accurso, E Main, A Prasad, C Schans, P Mccormack, P Burnham, K Southern, M Mcilwaine, L Wong, M Chilvers, S Miller, D Hall, C Clayton, A Lee, A Burge, A Holland, A Lee, A Burge, A Holland, E Polverino, P Goeminne, M Mcdonnell, L Myers, S Horn, J Abbott, M Dodd, D Bilton, A Webb, L Morrison, S Milroy, T Radtke, L Boni, P Bohnacker, G Sokol, D Vilozni, R Hakimi, E Wallaert, T Perez, A Prevotat, E Bernard, L Israel, M Debris, P Flume, C Strange, X Ye, M Mcilwaine, B Button, K Dwan, J Bradley, F Moran, J Elborn, T Volsko, C Oermann, P Swank, M Sockrider, Giovannetti, L Morin, M Gaubert
Abstract
Airway clearance therapy is an important treatment strategy in patients with respiratory disease and impaired mucociliary transport (e.g. cystic fibrosis [CF]) Airway clearance techniques (ACTs) supplement the mucociliary clearance system in the presence of disease-related impairment [2], and are important for maintaining respiratory health Current airway clearance interventions are based mainly on physical or mechanical measures to move air behind mucosal obstruction, and modulation of expiratory airflow to enhance movement of secretions to more proximal airways for more effective clearance