SGLT inhibitors as antidiabetic agents: a comprehensive review
Rahul Kshirsagar, Abhishek Kulkarni, Rashmi S. Chouthe, Shahebaaz K. Pathan, Hemant D. Une, G. Bhanuprakash Reddy, Prakash V. Diwan, Siddique Akber Ansari, Jaiprakash N. Sangshetti
Abstract
Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review, we cover the scientific studies on sodium/glucose cotransporter (SGLT) inhibitors published during the last decade. Our focus on providing an exhaustive overview of SGLT inhibitors enabled us to present their chemical classification for the first time.
Topics & Concepts
Diabetes mellitusPharmacologyMedicineChemistryEndocrinologyDiabetes Treatment and ManagementPancreatic function and diabetesDiabetes Management and Research