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Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications

Rebecca Goldman, Namratha Turuvekere Vittala Murthy, Trent P. Northen, Anuranjani Balakrishnan, Sudha Chivukula, Hillary Danz, Timothy Tibbitts, Anusha Dias, Jorel Vargas, Dustin L. Cooper, Hardip Gopani, Angela Beaulieu, Kirill V. Kalnin, Timothy Plitnik, Saswata Karmakar, Ramesh Dasari, Ryan F. Landis, Shrirang Karve, Frank DeRosa

2023Biomaterials26 citationsDOI

Topics & Concepts

ChemistryIn vivoBiophysicsBiochemistryLiposomeLipid bilayerNanodiscHEPESLipid AMessenger RNABiologyMembraneImmunologyBiotechnologyLipopolysaccharideGeneRNA Interference and Gene DeliveryAnimal Virus Infections StudiesSARS-CoV-2 and COVID-19 Research
Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications | Litcius