Modulation of Local Cellular Activities using a Photothermal Dye-Based Subcellular-Sized Heat Spot
Ferdinandus Ferdinandus, Madoka Suzuki, Cong Quang Vu, Yoshie Harada, Satya Ranjan Sarker, Shin’ichi Ishiwata, Tetsuya Kitaguchi, Satoshi Arai
Abstract
for the induction of muscle contraction in C2C12 myotubes by heat release. We successfully showed heat-induced contraction to occur in a limited area of a single myotube based on the alteration of protein-protein interactions related to the contraction event. These results demonstrate that even a single heat spot provided by a photothermal material can be extremely effective in altering cellular functions.
Topics & Concepts
Photothermal therapyMicroscale chemistryBiophysicsFluorescenceMaterials scienceMyogenesisMicroscopyFluorescence microscopeNanoparticleNanotechnologyOpticsCell biologyMyocyteBiologyMathematicsMathematics educationPhysicsPhotoacoustic and Ultrasonic ImagingNanoplatforms for cancer theranosticsNeurobiology and Insect Physiology Research