A DFT/TD-DFT investigation of clozapine adsorption on B <sub>12</sub> Y <sub>12</sub> (Y = N, P) nanocages as vehicles for applications in schizophrenia treatment
Charly Tedjeuguim Tsapi, Stanley Numbonui Tasheh, Aymard Didier Tamafo Fouégué, Numbonui Angela Beri, Caryne Isabelle Lekeufack Alongamo, Emmanuel Dassi Atongo, Julius Numbonui Ghogomu
Abstract
nanocages as promising nanocarriers for targeted clozapine delivery, combining stable binding with the potential for efficient and controlled drug release and, however, warranting experimental validation for addressing current challenges in schizophrenia therapy.
Topics & Concepts
NanocagesClozapineAdsorptionSchizophrenia (object-oriented programming)Density functional theoryMaterials scienceChemistryPhysical chemistryComputational chemistryCatalysisPsychiatryOrganic chemistryMedicineBoron and Carbon Nanomaterials ResearchBoron Compounds in ChemistryRare-earth and actinide compounds