Tumor microenvironment responsive supramolecular glyco-nanovesicles based on diselenium-bridged pillar[5]arene dimer for targeted chemotherapy
Yang Wang, Ming Jin, Zelong Chen, Xianjun Hu, Liang Pu, Zhichao Pei, Yuxin Pei
Abstract
Supramolecular glyco-nanovesicles (SeSe-(P5)2⊃Man-NH3+) based on the host-guest complex of a diselenium-bridged pillar[5]arene dimer and a mannose derivative have been successfully developed for the first time, which possessed tumor microenvironment-responsiveness and specific targetability due to their diselenium bonds and mannose units, respectively.
Topics & Concepts
DimerSupramolecular chemistryPillarChemistryDerivative (finance)Tumor microenvironmentStereochemistryNanotechnologyTumor cellsCrystallographyMaterials scienceCancer researchCrystal structureBiologyOrganic chemistryEngineeringStructural engineeringFinancial economicsEconomicsSupramolecular Chemistry and ComplexesSupramolecular Self-Assembly in MaterialsNanoplatforms for cancer theranostics