Aptamer assisted CRISPR-Cas12a strategy for small molecule diagnostics
Chenqi Niu, Chuyi Wang, Fan Li, Xiang Zheng, Xin‐Hui Xing, Chong Zhang
Topics & Concepts
AptamerCRISPRTrans-activating crRNAMolecular probeChemistrySmall moleculeNucleic acidFluorophoreOligonucleotideMolecular beaconDNAComputational biologyBiosensorCombinatorial chemistryBiophysicsNanotechnologyFluorescenceGenome editingBiochemistryBiologyMolecular biologyPhysicsQuantum mechanicsMaterials scienceGeneCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery