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Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

John T. Crowl, Maximilian Heeg, Amir Ferry, J. Justin Milner, Kyla Omilusik, Clara Toma, Zhaoren He, John T. Chang, Ananda W. Goldrath

2022Nature Immunology244 citationsDOIOpen Access PDF

Topics & Concepts

EpigeneticsBiologyCytotoxic T cellDNA methylationCell biologyGeneticsGeneGene expressionIn vitroT-cell and B-cell ImmunologyImmune Cell Function and InteractionSingle-cell and spatial transcriptomics
Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments | Litcius