Metabolism in Invariant Natural Killer T Cells: An Overview
Emily L. Yarosz, Cheong‐Hee Chang, Ajay Kumar
Abstract
Cellular metabolism is critical for generating energy and macromolecules for cell growth and survival. In recent years, the importance of metabolism in mediating T cell differentiation, proliferation, and function has been a hot topic of investigation. However, very little is known about metabolic regulation in invariant natural killer T (iNKT) cells. In this viewpoint, we will discuss what is currently known about immunometabolism in iNKT cells and how these findings relate to CD4 T cells.
Topics & Concepts
Natural killer T cellCell metabolismMetabolismCell biologyCellular metabolismBiologyEnergy metabolismCell growthInvariant (physics)CellFunction (biology)T cellImmunologyImmune systemBiochemistryEndocrinologyPhysicsMathematical physicsImmune Cell Function and InteractionT-cell and B-cell Immunology